Written questions by Arthur.

Whether his Department has assessed whether NICE has approved a greater or fewer number of new medicines since the introduction of the severity modifier in 2020, compared with comparable international health systems.

The National Institute for Health and Care Excellence (NICE) is responsible for the methods and processes that it uses in the development of its recommendations. The severity modifier was introduced in January 2022 as part of a number of changes intended to make NICE’s methods fairer, faster and more consistent.NICE carried out a review of the implementation of the severity modifier in September 2024 and found that it is operating as intended with a greater proportion of medicines recommended than under NICE’s previous methods. Since then, NICE has continued to monitor how the severity modifier is being applied. The latest figures include data from technology appraisals published up until the end of September 2025 and show that the proportion of positive decisions has increased since the severity modifier was implemented and since data was published in September 2024. 87.0% of decisions taken since the severity modifier was implemented, compared with 82.5% when the end-of-life modifier was being used. NICE is also recommending a greater proportion of new cancer treatments overall, 86.3% compared to 75.0%, and advanced cancer treatments specifically, 84.8% compared to 69.1%.NICE has commissioned research to gather further evidence on societal preferences that will inform future methods reviews.

Whether his department has considered the impact of NICE’s severity modifier, introduced in 2020, on NHS England’s access to innovative cancer medicines which were previously eligible under the end-of-life weighting.

The National Institute for Health and Care Excellence (NICE) is responsible for the methods and processes that it uses in the development of its recommendations. The severity modifier was introduced in January 2022 as part of a number of changes intended to make NICE’s methods fairer, faster and more consistent.NICE carried out a review of the implementation of the severity modifier in September 2024 and found that it is operating as intended with a greater proportion of medicines recommended than under NICE’s previous methods. Since then, NICE has continued to monitor how the severity modifier is being applied. The latest figures include data from technology appraisals published up until the end of September 2025 and show that the proportion of positive decisions has increased since the severity modifier was implemented and since data was published in September 2024. 87.0% of decisions taken since the severity modifier was implemented, compared with 82.5% when the end-of-life modifier was being used. NICE is also recommending a greater proportion of new cancer treatments overall, 86.3% compared to 75.0%, and advanced cancer treatments specifically, 84.8% compared to 69.1%.NICE has commissioned research to gather further evidence on societal preferences that will inform future methods reviews.

Whether his Department made an impact assessment of the effect of NICE’s severity modifier, introduced in 2020, on the ability of cancer medicines to meet the new ‘high severity’ threshold for approval.

The National Institute for Health and Care Excellence (NICE) is responsible for the methods and processes that it uses in the development of its recommendations. The severity modifier was introduced in January 2022 as part of a number of changes intended to make NICE’s methods fairer, faster and more consistent.NICE carried out a review of the implementation of the severity modifier in September 2024 and found that it is operating as intended with a greater proportion of medicines recommended than under NICE’s previous methods. Since then, NICE has continued to monitor how the severity modifier is being applied. The latest figures include data from technology appraisals published up until the end of September 2025 and show that the proportion of positive decisions has increased since the severity modifier was implemented and since data was published in September 2024. 87.0% of decisions taken since the severity modifier was implemented, compared with 82.5% when the end-of-life modifier was being used. NICE is also recommending a greater proportion of new cancer treatments overall, 86.3% compared to 75.0%, and advanced cancer treatments specifically, 84.8% compared to 69.1%.NICE has commissioned research to gather further evidence on societal preferences that will inform future methods reviews.

What steps he is taking to increase collaboration between his Department and Drinkaware.

External engagement is a fundamental part of what United Kingdom ministerial Government departments do.  We recognise the importance of promoting transparency through engagement and the need to take a balanced and proportionate approach.In Fit for the Future: 10-Year Health Plan for England, the Government has committed to some crucial steps to help people make healthier choices about alcohol, for instance making it a legal requirement for alcohol labels to display health warnings and consistent nutritional information. The plan can be accessed online at the following link:https://www.gov.uk/government/publications/10-year-health-plan-for-england-fit-for-the-futureIn the development and progression of the 10-Year Health Plan’s commitments and other policies, Department officials have met a wide range of stakeholders and are making plans for further stakeholder engagement to take place shortly. Stakeholder insights will help shape the Department’s work to ensure that are policies are most effective.

What steps he has taken to help reduce sepsis mortality in patients with leukaemia and other cancers.

Sepsis has no specific diagnostic test, and the signs and symptoms can vary hugely across all patients, making sepsis challenging to diagnose early. It is therefore critical that all acutely unwell patients are treated promptly and appropriately regardless of cause.Screening, diagnosis, and treatment of suspected sepsis is supported by the use of the National Early Warning Score (NEWS2). NEWS2 supports clinicians to determine the need for immediate care and is used in 99% of acute National Health Service trusts and 100% of ambulance trusts in England.To further aid clinical staff in diagnosing sepsis early, the National Institute of Health and Care Excellence (NICE) has published national guidelines on the recognition, diagnosis, and early management of suspected sepsis in people aged 16 years old and over. People with a weakened immune system, such as those having chemotherapy treatment, are more likely to get an infection that could lead to sepsis. Therefore, NICE has additional guidelines on the prevention and management of neutropenic sepsis in people with cancer. NICE guidelines provide authoritative, evidence-based guidance on best practice and should be taken fully into account by healthcare professionals in the care and treatment of NHS patients. The guidelines can be accessed alongside NHS England’s online sepsis training programmes.Additionally, the Department continues to fund research through the National Institute for Health and Care Research, to improve our understanding of sepsis diagnosis and immediate management.The National Cancer Plan will have patients at its heart and will cover the entirety of the cancer pathway, from referral and diagnosis to treatment and ongoing care. It will seek to improve every aspect of cancer care to better the experience and outcomes for people with cancer. Our goal is to reduce the number of lives lost to cancer over the next 10 years.

What steps he is taking to ensure timely access to chemosaturation for patients with metastatic ocular (uveal) melanoma.

The Department remains committed to ensuring that cancer patients, including those with metastatic ocular melanoma, have timely access to treatment and tailored medical support.In 2016, NHS England concluded that there was insufficient evidence to make chemosaturation treatment available to patients on the National Health Service. NHS England is currently in the early stages of policy development for chemosaturation to treat metastatic uveal melanoma where surgery to remove or destroy affected cells and tissue in the liver is not feasible.The National Institute for Health and Care Excellence has published an Interventional Procedure Guidance for this treatment, and while this does allow NHS trusts to offer the treatment locally, they can only do so if they put in place special arrangements for clinical governance, consent, audit, or research, because further evidence of benefit and safety is needed. The 2016 NHS England Clinical Commissioning policy is currently under review, and we expect that a new draft policy will be shared with stakeholders over the coming months. If NHS England’s clinical panel makes the treatment routinely available across the NHS in England it will require further consideration through relative prioritisation and investment before full roll out.The development of a Clinical Commissioning policy will determine both if the evidence is now sufficient to enable making the treatment routinely available and, if it is, whether to allocate service development funding to implement it across the NHS in England.

What steps he is taking to help improve women's heart health.

The Government is committed to prioritising women’s health, and we are delivering our commitment that never again will women’s health be neglected.In 2023, 31% of those who died prematurely from cardiovascular disease (CVD) were women. We are committed to reducing premature mortality from heart disease and stroke by 25% in the next 10 years. To accelerate progress towards this ambition, we will publish a new CVD modern service framework in 2026. Officials and NHS England are working closely to deliver the framework and are engaging widely throughout its development.The NHS Health Check, a core component of England’s CVD prevention programme, aims to detect people at risk of heart disease, stroke, type 2 diabetes, and kidney disease in those aged between 40 and 74 years old. The programme prevents approximately 500 heart attacks or strokes annually and every year, approximately 770,000 women complete an NHS Health Check.Work to improve access to the NHS Health Check programme is ongoing, including the development of a NHS Health Check Online service, which will allow women to undertake their health check at home, at a time and place convenient to them.

What steps he is taking to improve the (a) treatment and (b) prevention of cardiovascular diseases that disproportionately impact women, including (i) Spontaneous Coronary Artery Dissection, (ii) Myocardial Infarction with Non-Obstructive Coronary Arteries and (iii) Takotsubo Cardiomyopathy.

In 2023, 31% of those who died prematurely from cardiovascular disease (CVD) were women. We are committed to reducing premature mortality from heart disease and stroke by 25% in the next 10 years through improvements in prevention and treatment.To accelerate progress towards this ambition, we will publish a new cardiovascular disease Modern Service Framework (CVD MSF) in 2026. The CVD MSF will support consistent, high quality and equitable care whilst fostering innovation across the CVD pathway.

What steps he is taking to publish guidance on managing hypoglycaemia that includes (a) treatment, (b) when to seek medical help and (c) rules for those with diabetes who drive or operate heavy machinery.

The National Institute for Health and Care Excellence has published advice on the management of type 1 diabetes, including advice on managing acute hypoglycaemia, which is available at the following link: https://cks.nice.org.uk/topics/diabetes-type-1/management/ There are no current plans for the Department to publish specific guidance for distinct workforce groups.

With reference to the report by Sarcoma UK entitled Unique Among Cancers: A state of the nation review of sarcoma care, published on 11 June 2025, what steps he plans to take to help tackle issues noted in that report relating to sarcoma (a) diagnosis, (b) treatment and (c) care.

The Department has received, and relevant officials are currently considering, Sarcoma UK’s report reviewing sarcoma care across the United Kingdom.The Department will get the National Health Service diagnosing cancer earlier and treating it faster, including sarcoma. To achieve this, the NHS in England has delivered an extra 40,000 operations, scans, and appointments each week as the first step to ensuring early diagnosis and faster treatment.NHS England has published a national service specification, covering both bone and soft tissue sarcomas. The specification requires close working between sarcoma services and other NHS partners, co-ordinated by Sarcoma Advisory Groups, to improve care pathways.The National Cancer Plan for England will have patients at its heart and will cover the entirety of the cancer pathway, from referral and diagnosis to treatment and ongoing care, as well as research and innovation. The plan will seek to improve every aspect of cancer care to better the experience and outcomes for all patient groups, including sarcoma patients.

What progress he has made on the establishment of Commercial Research Delivery Centres.

Significant progress has been made in establishing the United Kingdom-wide network of Commercial Research Delivery Centres (CRDCs). Since 1 April 2025, 21 CRDCs have been operating across all four nations of the UK, 15 in England, four in Scotland, and a one-nation approach in both Wales and Northern Ireland. These have been funded through the Voluntary Scheme for Branded Medicines Pricing, Access and Growth Clinical Trials Investment Programme, alongside National Institute for Health and Care Research funding in England.A UK-wide CRDC Network was launched on 1 September 2025 to coordinate activity, provide strategic leadership, and support consistency across the centres. To expand commercial research into out-of-hospital settings, 14 Primary Care CRDCs will begin on 1 November 2025 in England. These will be hosted by general practice-led NHS primary care organisations and fully integrated into the CRDC Network. Together, these initiatives will enhance the speed, consistency, and inclusivity of commercial clinical research delivery, strengthening the UK’s position as a global life sciences leader.

Whether he is taking steps to encourage smaller snack sizes.

There is no one specific government policy to encourage the availability of smaller snack sizes, but through the 10-Year Health Plan the government is taking a whole diet approach and focussing on the key drivers that encourage overconsumption of less healthy food and drink, as part of its mission to tackle obesity.The Department is taking several actions to improve diets and reduce the consumption of calories and other ingredients of concern, such as saturated fat, salt and sugar. This includes the introduction of mandatory healthy sales reporting for large food businesses by the end of this Parliament; and the setting of new targets to increase the healthiness of sales for the largest food businesses. This will set full transparency and accountability around the food and drink that businesses are selling and should encourage an increase in sales of healthier products. Businesses will have the freedom to decide how they achieve the target, with reformulation of existing products and the introduction of new healthy products forming options for businesses to make healthier options accessible for all.In addition, the Volume Price Promotions regulations came into force on 1 October 2025, restricting volume promotions such as “buy one get one free” and “3 for £10” on less healthy food and drink. Mandatory restrictions on the advertising of less healthy food and drink on TV and online are due to come into force on 5 January 2026. However, since 1 October 2025, advertisers and broadcasters have been voluntarily complying with the restrictions ahead of them taking legal effect next year. We are already seeing a change in the type of adverts shown on TV and online. These policies are in addition to the locations promotions legislation which came into effect in 2022 and prevent less healthy products being placed in certain locations in supermarkets that lead to uplifts in purchasing.All these policies are designed to encourage the food industry to make the products they sell healthier. Information is also available to help people make better choices. Better Health Families uses personalised email programmes, digital and social media to help families with primary school aged children to eat healthier snacks including suggestions on fruit, vegetable and homemade snacks and choosing healthier snacks while shopping.

Pursuant to the Answer of 16 September to Question 75570 on Alcoholic Drinks: Labelling, when he plans to consult with stakeholders on the best ways to communicate the necessary information on the health risks to consumers through alcohol labels.

In the 10-Year Health Plan, the Government committed to strengthen and expand on existing voluntary guidelines for alcohol labelling by introducing a mandatory requirement for alcoholic drinks to display consistent nutritional information and health warning messages. The Plan is available at the following link:https://www.gov.uk/government/publications/10-year-health-plan-for-england-fit-for-the-futureDepartmental officials are currently formulating plans for stakeholder engagement and a formal consultation. The timeline will be confirmed in due course. Stakeholder insights will help shape the policy to ensure the labelling requirements are most effective.

Whether he has considered introducing national guidance on the potential physical health risks of excessive screen time for children and young people.

In 2019, the UK Chief Medical Officers published a commentary on the findings of a systematic review on screen-based activities and children’s mental health. This commentary included advice for parents and carers on agreeing boundaries with children and young people on time spent using screens outside of school and educational use. The commentary is available at the following link: https://assets.publishing.service.gov.uk/media/5c5b1510e5274a316cee5be8/UK_CMO_commentary_on_screentime_and_social_media_map_of_reviews.pdfFurther research examining the causal relationship between screentime and children’s physical and mental health and how it might be mediated is welcomed. The Department has no plans to publish additional guidance on screentime and children’s health at this time, but departmental policies will remain agile to emerging and future research.

Whether HPV self-sampling will be less frequently than clinician screening, in the context of uncertainties in relation to the accuracy of the self-sampling test.

The frequency of human papilloma virus (HPV) self-sampling will be the same as the frequency of clinician-led cervical screening. The home kits will only be offered to people who have missed their cervical screening appointment by six months or more. The next stage in the pathway for anyone who tests positive for HPV via self-sampling would be an appointment for a clinician-taken test.Following the announcement to introduce HPV self-sampling in the National Health Service cervical screening programme for the under-screened population, the NHS has begun planning an in-service evaluation (ISE) of HPV self-sampling in the wider population.The purpose of the ISE is to ensure that the self-sampling test is acceptable, accurate, and feasible compared with a clinician collected specimen, and to evaluate its impact on cervical screening uptake. The findings of the ISE will inform any future UK National Screening Committee recommendation to ministers to offer self-sampling across the whole population, alongside clinician-led screening.

Whether his Department has made an assessment of the potential merits of offering additional resources to neighbourhood teams to provide targeted interventions enabling equitable access to (a) HPV vaccination and (b) cervical screening.

As part of our 10-Year Health Plan, we have recently launched the National Neighbourhood Health Implementation Programme, to support systems with the roll-out of neighbourhood health services which will bring together teams of professionals, including pharmacists, to work together to provide comprehensive care in the community.The Department is working with NHS England and the UK Health Security Agency to encourage high uptake of all immunisation and screening programmes, including in areas where coverage has historically been low, by exploring new, accessible, and innovative delivery models.The Department is also working with partners to develop options for human papillomavirus (HPV) catch-up vaccination through community pharmacies from 2026, with the ambition to increase the accessibility and uptake of HPV vaccinations among younger adults who have left school, supporting our aim to eliminate cervical cancer by 2040.For cervical screening, primary care networks collaborate across their local neighbourhoods to offer additional appointments to improve access and convenience. Regional commissioners and providers also undertake targeted outreach campaigns. For example, the Living Well initiative in Cheshire and Merseyside offers mobile cervical screening to eligible individuals. The service can reach more individuals by being closer to where people live, work, and shop.NHS England has also increased the provision of cervical screening sample taking services in integrated sexual health settings, which in turn has helped to improve access for people eligible for screening, especially individuals who would not access general practice or are not registered with a general practice.

What progress his Department has made on re-establishing a central capacity for co-ordinating preventative mental health work.

The 10-Year Health Plan sets out ambitious plans to transform mental health services to improve access and treatment, and to promote good mental health and wellbeing for the nation. This includes improving assertive outreach, investment into mental health emergency departments, increasing access to evidence-based digital interventions, and providing mental health support teams in schools and colleges. The Department recognises that there have been changes to the public health capacity and capability at a national, regional, and local level in recent years. However, the Government is committed to working beyond the health system to create an environment that promotes good mental health, prevents people from developing mental health problems, and improves the lives of people living with a mental health problem. Further work is required across the Government to create the conditions for good mental wellbeing, alongside early intervention and recovery to support people to live well in their communities and thrive.

What steps he is taking to increase the availability of donors for stem cell transplants.

The United Kingdom aligned stem cell registry (a national register managed collaboratively by Anthony Nolan, DKMS UK, NHS Blood and Transplant and the Welsh Bone Marrow Donor Registry) has over 2.3 million potential stem cell donors registered.The Department is taking action to increase the number of people on the UK aligned stem cell registry through funding the DHSC Stem Cell Programme (£2.4 million for the period 2022-25). The programme is being delivered by NHS Blood and Transplant (NHSBT) and Anthony Nolan. It aims to enhance the resilience of the UK's stem cell supply by strategically recruiting donors to the UK aligned stem cell registry. It focuses on recruiting those most likely to donate, and on addressing health disparities through targeted campaigns, with a focus on ethnic minority communities.By increasing the pool of potential donors, the programme seeks to improve the availability of matches in the UK, ultimately reducing waiting times for patients in need of stem cell treatment. Funding to both organisations has been extended by 1 year (2025/26).

What discussions he has had with the Secretary of State for Culture, Media and Sport on the role of industry advertising in reducing the rate of alcohol harms.

As highlighted in the Fit for the Future: 10-Year Health Plan for England, the Government recognises that alcohol harms are increasing in the United Kingdom, and that to help tackle these harms a multi-faceted approach that includes prevention, harm reduction, and treatment is required.In the plan, the Government has committed to increasing the awareness of the harms by introducing a mandatory requirement for alcoholic drinks to display consistent nutritional information and health warning messages.There are several pieces of research underway which will strengthen the evidence base on the impact of alcohol marketing on the levels of consumption and the associated harms. Alongside the Department for Culture, Media and Sport, we will consider this new evidence when it is available.

Whether he plans to publish a timeline for strengthening voluntary guidelines for alcohol labelling.

In Fit for the Future: 10 Year Health Plan for England, the Government committed to strengthening and expanding existing voluntary guidelines for alcohol labelling by introducing a mandatory requirement for alcoholic drinks to display consistent nutritional information and health warning messages. The plan can be accessed on the GOV.UK website, at the following link: https://www.gov.uk/government/publications/10-year-health-plan-for-england-fit-for-the-future Department officials are progressing this work at pace and, at the appropriate time, we will consult with stakeholders on the best ways to communicate the necessary information on the health risks to consumers through alcohol labels. The timeline for implementing mandatory alcohol labelling is yet to be determined, and will take into account the full range of stakeholder views and consultation responses.